To learn more about cholesterol and heart disease, read Managing Your Cholesterol, a Special Health Report from Harvard Medical School. Grapefruit juice affects certain statins more than others. I am on Lipitor or Atorvastatin for years and have same problem and just loved my grapefruit for special breakfasts Susan Duchesne. Drug interactions with common fruits, fruit juices, and beverages such as grapefruit and grapefruit juice, and caffeine are discussed. But to be on the safe side, check with your doctor, and avoid taking your pills with grapefruit juice. I think that pertains to real grapefruit or grapefruit juice not flavoring. What's more, eating half a grapefruit is even less risky than drinking grapefruit juice, since it takes several fruits to make a single glass of juice. That's because the studies showing dangerous effects used massive amounts of furanocoumarins, the amount found in a quart or more of the juice. But if you can't switch, experts say it's probably okay to enjoy a small glass. CBD is similar to grapefruit in that it also binds with those enzymes, but research suggests that it’s possibly. Takeaway Eating grapefruit may negatively interact with certain statin drugs, such as atorvastatin, lovastatin, and simvastatin. Not all statins are affected equally by grapefruit juice, so grapefruit fans might want to switch to a statin that's less affected (see the table below). That elevates risk of having dangerously high levels of the drug in your system. As a result, more of the drug is absorbed, making it more powerful than it's meant to be - even toxic in some cases. Grapefruit juice can increase the blood levels of atorvastatin. Also, avoid excess alcohol use, as this may cause serious liver problems. You should avoid large quantities of grapefruit or grapefruit juice, which can increase the risk of serious side effects. Specifically, drinking grapefruit juice will result in higher levels of. Children 6 to 11 years: 325 mg every 4 to 6 hours maximum daily dose. While taking atorvastatin ( Lipitor ), avoid high-fat and high-cholesterol foods as part of your overall treatment. Grapefruit juice contains compounds called furanocoumarins that stop CYP3A from doing its job. Grapefruit juice affects the normal processing of Lipitor (atorvastatin) by the liver. Why?Ī: Certain classes of drugs - most notably statins - are metabolized (broken down) in your intestines by an enzyme called CYP3A, which normally reduces the amount of drug that enters your bloodstream. Q: I've heard that people shouldn't drink grapefruit juice if they're taking a statin.
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